Liquid Biopsy and Oncology

ctDNA Standards For Amplicon-based Assays

AM Normal Cell Free gDNA

ctDNA Standard for Capture-Based NGS

cfDNA Extraction Sensitivity Controls

RNA Fusion Control

cfDNA Extraction Specificity Controls

Figure-B

Multiplexed ctDNA fragments (~150bp) mixed with nucleosomally fragmented wildtype cfDNA background in human plasma. The cell-derived ctDNA fragments are generated by Anchor’s unique multiplexed gene-editing method and are nucleosomally fragmented to around 150bp. The cell-derived variants are suitable for both the amplicon-based and capture-based methods. The synthetic ctDNA fragments are gBlocks-like dsDNA of 150-170bp and are suitable for amplicon-based applications, including ddPCR, qPCR, and amplicon-based NGS.

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AM Normal cfgDNA-1
Description: DNA is extracted and fragmented from a popular normal male cell line

Product NameCat. No.Size (vial)
AM Normal cfgDNA-1 (Dissolved in TE)601330011ug per vial
AM Normal cfgDNA-1 (Spiked in Plasma)60133501Pre-spiked with 125ng gDNA per 5ml

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Twenty-three Multiplexed nucleosomally fragmented ctDNA fragments (~150bp) mixed with normal patient cfDNA background in human plasma. The cell-derived ctDNA fragments are generated by Anchor’s unique multiplexed gene-editing method and are nucleosomally fragmented to around 150bp. The cell-derived variants are suitable for capture-based methods.

For customer SNV/indel/fusion variants for either cfDNA assays or solid tumor tests, please request by clicking the “Order Here” button and select the “Customer Molecular Controls” option.

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Does your cfDNA extraction process affect the Limit of Detection (LOD) of a particular gene target? Our new products, cfDNA Extraction Sensitivity Panels and Extraction Low Positive Controls, can help your research and development for liquid biopsy assays.

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For customized fusion solutions, please contact us at: info@anchormolecular.com
+1 925-400-9986 for ordering

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The Plasma Genomic cfDNA Extraction Control is for the purpose of monitoring the degree of genomic DNA (gDNA) contamination in the extracted cfDNA. DNA-free plasma is spiked with either with high molecular weight gDNA molecules or 170 bp cfDNA fragments or both.

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